The kings of the web world are also the dominant forces of media in general, according to the MediaGuardian 100 list.
Facebook founder Mark Zuckerburg was named the most powerful man in the UK's media, followed by Twitter co-creator Jack Dorsey.
In third was Google's Larry Page, with Apple's Steve Jobs in fifth and Amazon's Jeff Bezos in 11th.
Google managed two entrants in the top 100 list, with Android founder Andy Rubin coming in 44th.
"[He is] increasingly confident as a public speaker, and supported by a team of charming and extremely skilled executives that include chief operating officer Sheryl Sandberg," the Guardian said.
"Zuckerberg will remain the most influential figure in technology in a company that only ever looks onwards and upwards."
Facebook could face problems in the future, however, and will have to prove it can deliver on its advertising promises to make some money, the publication said.
"With a public offering expected early in 2012 at a valuation that could be more than $100 billion Facebook has yet to put some serious money where its mouth is," the Guardian added.
In Millward Brown's recent list of the world's most valuable brands, technology companies dominated again.
Apple came in top, with Google in second, IBM third and Microsoft fifth.
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