AMD takes the wraps off new Instinct MI300X chips for AI workloads
The data center-focused hardware will enable customers to run high-performance AI and HPC workloads

New AMD Instinct MI300X and MI300A chips are now available to customers through a number of OEM partners.
The chips are intended to help underpin organizations wanting to build their own hardware on which to run artificial intelligence (AI) workloads and train large language models (LLMs).
The MI300X accelerators in particular have high memory bandwidth – which AMD claims to be “industry leading” in performance tests versus the published performance of rival chips – and is optimized for LLM training and inferencing. Compared to previous generation AMD Instinct MI250X accelerators, the MI300X, which are powered by AMD CDNA3 architecture, deliver 1.5 times more memory capacity, 1.7 times more peak theoretical capacity, and 40% more compute workloads.
The MI300A, meanwhile, is an accelerated processing unit (APU) that uses AMD’s 3D packaging and 4th generation Infinity Architecture and combines AMD CDNA 3 GPU cores with Zen 4 CPUs, and 128GB of HBM3 memory. According to AMD, the MI300A delivers approximately 1.9 times the performance-per-watt on FP32 HPC and AI workloads versus the Instinct MI250X.
Current OEM partners offering products containing MI300X and MI300A chips include:
- Dell Technologies, which showcased the Dell PowerEdge XE9680 server containing eight AMD Instinct MI300 Series accelerators at AMD's Advancing AI event in December.
- Hewlett Packard Enterprise (HPE). Its Cray Supercomputing EX255a supercomputing accelerator blade, shown at the same event, is the first to be powered by AMD Instinct MI300 APUs.
- Supermicro. Its new H13 generation of accelerated servers features AMD Instinct MI300 Series accelerators and 4th generation AMD EPYC CPUs.
- Oracle, which plans to add AMD Instinct MI300X-based instances to support its Oracle Cloud Infrastructure (OCI) Supercluster with ultrafast RDMA networking.
RELATED RESOURCE
Choose an optimal solution that satisfies your computing needs
“AMD Instinct MI300 Series accelerators are designed with our most advanced technologies, delivering leadership performance, and will be in large scale cloud and enterprise deployments,” said Victor Peng, president of AMD.
“By leveraging our leadership hardware, software and open ecosystem approach, cloud providers, OEMs and ODMs are bringing to market technologies that empower enterprises to adopt and deploy AI-powered solutions.”
Get the ITPro daily newsletter
Sign up today and you will receive a free copy of our Future Focus 2025 report - the leading guidance on AI, cybersecurity and other IT challenges as per 700+ senior executives
ITPro is a global business technology website providing the latest news, analysis, and business insight for IT decision-makers. Whether it's cyber security, cloud computing, IT infrastructure, or business strategy, we aim to equip leaders with the data they need to make informed IT investments.
For regular updates delivered to your inbox and social feeds, be sure to sign up to our daily newsletter and follow on us LinkedIn and Twitter.
-
Bigger salaries, more burnout: Is the CISO role in crisis?
In-depth CISOs are more stressed than ever before – but why is this and what can be done?
By Kate O'Flaherty Published
-
Cheap cyber crime kits can be bought on the dark web for less than $25
News Research from NordVPN shows phishing kits are now widely available on the dark web and via messaging apps like Telegram, and are often selling for less than $25.
By Emma Woollacott Published
-
How IT decision makers can prepare for the AI Age
Supported Content Whether it’s the hardware in your office or what’s powering your virtual machines, the right processors are the key to success
By Bobby Hellard Published
-
Why the CPU you chose is the key to Windows 11
The end of Windows 10 is on the horizon – it’s time to upgrade to an fTPM-protected processor
By Bobby Hellard Published
-
AMD Advancing AI live: All the news and updates as they happened
Live Blog ITPro has been live on the ground at the AMD Advancing AI conference in San Francisco this week – here's everything we learned in the big keynote with CEO Lisa Su
By Ross Kelly Last updated
-
What SMEs can learn from the supercomputing revolution
Sponsored Supercomputing may seem out of reach for the SME, but there are many best practices and technologies filtering down that are worthy of emulation
By ITPro Published
-
What medium and large enterprises can learn from the supercomputing revolution
Sponsored Supercomputing is leading the way with GPU acceleration and power consumption, which medium and large enterprises can emulate during digital transformation
By ITPro Published
-
What we can learn from the supercomputer revolution
Sponsored The fastest systems in the world have plenty to teach us about energy efficiency, security and the benefits of using common platforms
By ITPro Published
-
The benefits of a hardware update for SMBs
Sponsored Nobody loves a server refresh, but the benefits far outweigh the effort and the cost
By ITPro Published